🩸 Thyroid & Hormone Balance

Thyroid Support (+) - designed to optimize thyroid function, promote the conversion of T4 to T3, activate mitochondria, and support a healthy metabolic rate.

Supports thyroid hormone synthesis and regulation: the site states it “maintains a healthy balance of thyroid hormone synthesis and function.”

Promotes conversion of T4 → T3: this is critical, since a large portion of active T3 derives from peripheral conversion of the prohormone T4 (or from the gland itself) via deiodinase activity. Thyroid support formulas often include nutrients/cofactors that support deiodinases (selenium, zinc, etc.). The copy specifically claims “Promotes the Conversion of T4 to the More Active T3 Hormone.”

Supports mitochondrial activation and metabolic rate: thyroid hormones are key regulators of mitochondrial biogenesis and metabolic rate. By enhancing mitochondrial activation, this formula may help the downstream “engine” of thyroid hormone action (energy, thermogenesis, cellular metabolism) rather than purely glandular hormone output. The product statement: “Supports the Activation of Mitochondria: Enhances mitochondrial function, boosting energy production and promoting metabolic health.” 

Supports the HPT axis: “Balances the hypothalamus-pituitary-thyroid axis.” This means supporting regulatory feedback loops (TSH/thyroid hormone interplay) rather than just output.

TG (Thyroid Gland) 100 - How it can help thyroid function:

Glandular (thyroid tissue) supplements are based on the principle of providing bovine (or porcine) thyroid gland tissue to supply naturally occurring thyroid-specific proteins, enzymes, and trace nutrients (in the context of functional/integrative medicine). In your coaching language you might consider that it helps the thyroid “raw material” or “substrate” availability, perhaps supporting glandular structure, enzyme richness, or signaling that the thyroid tissue can draw upon.

With glandular exhaustion (chronic stress, long-term autoimmunity, low thyroid output) a thyroid glandular could serve as a support for tissue integrity, helping the gland recover capacity rather than only supplying exogenous hormone.

Because it is tissue-based (glandular) it may provide micro-nutrients and endogenous thyroid peptides that help the gland’s responsiveness to TSH and to upstream signals (TSH, TRH, adrenal/cortisol interplay).

Adrenal Cortex 100 mg - Although not a direct thyroid hormone supplement, this adrenal cortex glandular plays a key role in the broader endocrine and stress-metabolic environment that influences thyroid function. Here’s how:

The adrenal glands (via the HPA axis) and the thyroid (via the HPT axis) are intimately linked: chronic stress elevates cortisol, which can suppress the conversion of T4 to T3, increase conversion to reverse T3 (rT3), blunt TSH responsiveness, and impair thyroid receptor sensitivity. Supporting adrenal cortex/glandular can help rebalance the HPA axis, reduce cortisol overload, and thus create a more favourable environment for thyroid hormone activation and receptor function.

Glandulars of the adrenal cortex may provide bio-active peptides, nucleic acids, and enzymes that support adrenal integrity and output. The product may thus help energy, resilience, stress regulation, and indirectly support thyroid function (given thyroid’s sensitivity to stress).

Consider that a “stressed adrenal → poor conversion, elevated rT3, high cortisol → thyroid slows down” path is common. Therefore supporting adrenal strength can be considered part of the “twin engine” (adrenal + thyroid) approach.

DNA Prime - Supports Telomere Length and Telomerase Activity. While not a traditional “thyroid support” supplement, DNA Prime fits within your broader biochemical frame of detox, mitochondrial optimization, redox balance, and endocrine resilience. Here’s how it links:

Thyroid hormone function is deeply interconnected with mitochondrial function — T3 increases mitochondrial respiratory capacity, drives uncoupling, and supports basal metabolic rate. By improving mitochondrial function and cellular energy machinery (as DNA Prime claims), you amplify the “effectiveness” of thyroid hormone downstream (i.e., receptor and post-receptor signalling).

Oxidative stress (ROS) and DNA damage can impair endocrine glands (thyroid, adrenal) and disrupt deiodinase enzymes, thyroid receptor sensitivity, and cellular responsiveness to thyroid hormones. DNA Prime’s antioxidant/repair support helps the “substrate” on which thyroid hormones act.

Especially with high toxic burden (heavy metals, EMF/graphene oxide, chronic inflammation) you often see impaired thyroid conversion and signalling not due to low T4/T3 alone but due to mitochondrial dysfunction and oxidative load. DNA Prime supports that layer of the system, enhancing the context for thyroid hormone function.

So, in your multi-layer model: “Glandular integrity → hormone synthesis → conversion → receptor/mitochondrial responsiveness → metabolic effect.” DNA Prime supports the last two layers (conversion efficiency and mitochondrial responsiveness/repair) indirectly improving thyroid function.

Selenium 90 tabs - one of the most important micronutrients for thyroid health; there is strong research backing. Key mechanisms:

Selenium is required for iodothyronine deiodinases (the seleno-enzymes that convert T4 → T3) and to clear the hydrogen peroxide (H₂O₂) generated in thyroid hormone production via glutathione peroxidases (selenoproteins). 

Selenium deficiency has been shown to impair T4 to T3 conversion and increase reverse T3 (rT3) accumulation.

In autoimmune thyroiditis (e.g., Hashimoto’s thyroiditis) selenium supplementation has been associated with reduced thyroid antibodies (anti-TPO) and lower TSH in some studies.

Cautions & Notes:

Thyroid hormone conversion and receptor sensitivity are complex: heavy-metal burden, EMF/graphene oxide exposure, methylation bottlenecks, sulfation/glucuronidation, stress/adrenal load, gut dysbiosis (which influences deiodinase and reverse T3), liver detox capacity—all interplay. These products are supports, not replacements for that system work.

Glandulars (TG & Adrenal) may not be appropriate in certain autoimmune flare states or if there’s elevated thyroid antibody activity without stabilization — monitor accordingly.

High doses of selenium beyond safe limits can lead to adverse effects; ensure you know the exact dose per tab and total selenium exposure (diet + other supplements).

DNA Prime is more of a “system optimization” supplement rather than direct thyroid “fix.” Use it in the correct layer (after foundational supports are in place) and manage expectations accordingly.